Premier League Betting Tips: 20-22 December 2025

Key takeaways

• Premier League fixtures dominate with Spurs–Liverpool and Arsenal–Everton
• Injuries and suspensions create betting angles across Europe
• Form charts hint at goals in Leipzig v Leverkusen
• Juventus look stretched against title‑chasing Roma
• Real Madrid face Sevilla without several key players

Betting tips for 20–22 December 2025

Spurs v Liverpool: North London wobble versus Merseyside momentum

Tottenham’s new era under a new manager hit the buffers with a 3‑0 humbling at Nottingham Forest and just one win in seven league games. Injuries to key midfielders and full backs, and suspensions to holding players, leave their midfield and defence threadbare. Liverpool, by contrast, are buoyed by a 2‑0 win over Brighton thanks to a forward’s brace and have climbed into European contention. They aren’t at full strength either – several midfielders and defenders are sidelined and their star winger departs for the Africa Cup of Nations – but the Merseyside outfit look sharper.

• Tip: Both teams to score. Spurs still create chances at home, while Liverpool’s attacking edge should exploit the weakened Spurs back line.

Everton v Arsenal: Gunners top, but patched up

Table‑topping Arsenal cling to a five‑point lead thanks to Wolves’ own goals in a nervy 2‑1 win. However, defensive injuries are piling up; an injury to a starting centre‑back and fitness concerns for another defender leave the manager short at the back. Everton aren’t full strength either: three key first‑teamers are out, while two young defenders are just returning to training. The Merseyside outfit may try to frustrate the Gunners.

• Tip: Arsenal to win & under 3.5 goals. Everton’s resilience could keep the scoreline modest, but Arsenal’s quality should prevail.

Newcastle v Chelsea: Battle of the patched‑up squads

This Tyneside lunchtime kick‑off pits two injury‑hit squads. Newcastle are without several defenders, while their goalkeeper is a doubt. Chelsea are also depleted; they have multiple long‑term injuries in defence and midfield. Both sides have attacking talent, but their thin defences could mean open play.

• Tip: Over 2.5 goals. The mixture of attacking flair and defensive absentees suggests a high‑scoring affair.

Manchester City v West Ham: Chasing Arsenal, minus key stars

City eased past Crystal Palace but were missing several key attackers and midfielders through injuries. It is expected that their pacey winger will be out until the new year, and the club will manage a key midfielder’s hamstring carefully. West Ham travel without their suspended playmaker and injured goalkeeper. The east Londoners may sit deep and counter, while City push forward.

• Tip: City win to nil. West Ham’s creative absences could limit their threat, and even a depleted City usually control games at home.

Aston Villa v Manchester United: Fortress Villa Park

Villa are flying with nine successive wins and impressive victories over Manchester City and Arsenal. By contrast, United’s chaotic 4‑4 draw with Bournemouth hints at defensive frailty, and they could be without six players due to AFCON call‑ups, suspensions and defensive injuries. It’s a daunting trip for the visitors.

• Tip: Aston Villa to win. Home form and United’s defensive absentees point towards another Villa victory.

RB Leipzig v Bayer Leverkusen: Bundesliga top‑of‑the‑table tussle

Leverkusen are vying for the Bundesliga summit, but both sides are carrying knocks. RB Leipzig welcomed two squad players back to training midweek, yet several attackers and defenders remain sidelined and one versatile wing‑back is training individually. They also lose two midfielders to the African Cup of Nations. Leverkusen’s predicted line‑ups show they are missing a suspended defender and several injured squad members. Goals have flowed in recent meetings.

• Tip: Both teams to score. Offensive quality on both sides outweighs the defensive disruptions.

Real Madrid v Sevilla: Los Blancos threadbare

Real Madrid scraped a 2‑1 win over Alaves but suffered a rash of suspensions. Three players were sent off, and a regular full‑back is suspended while recovering from knee surgery. Their regular left‑back remains out for the year, and a young midfielder only just returned to training. Sevilla are inconsistent but may smell blood.

• Tip: Under 2.5 goals. Expect a cagey encounter with Madrid shuffling their line‑up and Sevilla likely to sit deep.

Juventus v Roma: Injury‑hit Old Lady hosts title challengers

Juventus are rebuilding but have been dealt major blows. Their centre‑back tore a knee ligament and will miss the match, while their main striker faces months out after surgery. An influential midfielder is suspended and another forward is doubtful. Roma have eyes on the Scudetto and travel without a suspended full‑back and a couple of attacking players.

• Tip: Roma or draw. Juventus’ absentees make them vulnerable, while Roma have momentum.

Fulham v Nottingham Forest (22 Dec): Relegation six‑pointer

This Monday night contest pits two sides fighting to steer clear of the drop. Fulham’s attacking talisman has been inconsistent and they’ve struggled for goals, while Forest recently thrashed Tottenham but still leak chances. In these tense scraps, discipline can prove decisive.

• Tip: Under 2.5 goals. Expect nerves to keep it tight.

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